Pro WS C422-ACE

    Pro WS C422-ACE

    Intel ATX LGA 2066 Workstation motherboard with PCIe 3.0 x16, 14 power stages, triple M.2 with dual M.2 heatsinks, dual U.2, dual Intel LAN, DDR4 ECC memory support, and ASUS Control Center Express

    • Ready for the latest Intel® Xeon® W workstation Processors
    • Three PCIe 3.0 x16 slots with optimized lane arrangement of 3-way x16/x16/x8 to accelerate an increasingly diverse array of workloads
    • Enhanced power solution: 12+2 IR3555 power stages, ProCool II connectors, alloy chokes, durable capacitors and 8-layer PCB design for stable power delivery
    • Ultrafast data-transfer speed with triple M.2 slots with two integrated heatsinks and dual U.2 slots for NVMe storage
    • ASUS Control Center Express: Server-grade IT management software featuring remote management and an intuitive interface
    • Server-grade quality with reliability testing to ensure optimized, 24/7 operation in various environments
    • Next-gen USB 3.2 Gen 2 connectivity delivers speeds of up to 10Gbps via Type-A and Type-C ports
    Product Image

    ASUS Pro Workstation motherboards are designed for professionals in AI training, deep learning, animation, 3D rendering or media production. Featuring expandable graphics, extensive storage, impressive connectivity and exceptional overall performance and reliability, Pro Workstation motherboards are the ideal solution for creative professionals. Each motherboard includes centralized management software, so they're also an efficient and cost-effective option for IT administrators.

    1 USB 2.0

    2 USB 3.2 Gen2 Type A

    3 USB 3.2 Gen2 Type-C

    4 Intel® I219-LM

    5 Intel® I210-AT

    6 8-CH Audio

    7 PCI Express 3.0
    3-Way SLI™
    3-Way Crossfire™
    Crystal Sound 3
    • Realtek® S1220A
    • Japanese made
      audio capacitors

    9 MOS HS + heat-pipe

    10 12+2 Power Stages

    11 ProCool II connector

    12 Intel® Socket 2066 for
    Intel® Xeon® W Processors

    13 M.2 (22110, PCIE 3.0 x4 & SATA)

    14 8 DIMM, Max. 512GB, DDR4

    15 6 x SATA 6Gbps ports

    16 M.2 (22110, PCIe 3.0 x4)

    17 Intel C422 chipset

    18 2 x U.2 (NVMe support)

    19 4 x front USB 3.2 Gen1
    4 x front USB 2.0

    Multi-GPU support

    Multi-GPU support

    Fully loaded takes on new meaning when you have up to 48 PCI Express® lanes and those lanes can be split in a 3-way x16/x16/x8 configuration spanning the board's trio of PCIe x16 slots, allowing you to load up on GPUs to accelerate an increasingly diverse array of workloads, including AI training, 3D rendering, and scientific or financial modeling.

    ASUS 2-WAY VGA holder

    User-friendly design

    The Pro WS C422-ACE is packed with an exclusive two-way VGA holder to provide extra rigid support for up to two high-end graphics cards, to prevent potentially damaging bowing or bending. This VGA holder is easy to install and can be mounted with an additional system fan (up to 120mm), making sure your workstation has ample cooling to complete any task.

    *Recommended maximum graphics card size: up to 12.90 x 5.90cm (length x depth)
    Power delivery enhancements

    Power delivery enhancements

    Pro WS C422-ACE provides stable power delivery to ensure optimal performance with the latest 18-core Intel® Xeon® W Processors.

    • ProCool II power connector
    • Power stages with IR3555 design
    • Alloy chokes
    • Durable capacitors
    • 8-layer PCB design

    ProCool II power connector

    The latest ProCool II is an enhanced EATX 8-pin power connector that offers higher endurance and longer lifespan by lowering impedance to prevent hotspots and connector failure. The new design includes upgrades to metal amour and solid pins for better dissipation, as well as a warning LED display with a BIOS POST message to indicate an improper connection.

    Enhanced Solid Pin
    Last-gen Hollow Pin

    Power stages with IR3555 design

    The CPU VRM on Pro WS C422-ACE employs a 12+2 power stage design with IR3555, combining high-side and low-side MOSFETs and drivers into a single package, delivering the power and efficiency that high core count processors demand.

    Alloy chokes

    The Pro WS C422-ACE series uses efficient alloy chokes and high-quality thermal pads to help transfer heat from the VRM array to a sink with ample surface area for the processors.

    Durable capacitors

    Durable capacitors are engineered to resist extreme temperatures and provide up to 110% better performance than the industry standard.

    8-layer PCB design

    Multiple PCB layers shift heat away from critical components, providing more headroom to push your CPUs beyond stock speeds.

    Tune it your way
    Triple M.2

    Triple M.2

    With x4 PCI Express 3.0 bandwidth, Pro WS C422-ACE comes with three onboard M.2 slots — including one vertical slot — that support up to 32Gbps data-transfer speeds. The slots feature ultra-efficient, dual heatsinks that reduce M.2 SSD temperatures by up to 18.7°C for optimal storage performance and improved SSD longevity.

    Dual U.2

    Unleash NVMe storage devices with dual U.2 ports to experience data-transfer speeds of up to 32Gbps and free up a PCIe slot for another expansion card.

    Upgrade your RAID

    Intel Virtual RAID on CPU (VROC) obliterates PCH-based RAID arrays that are bottlenecked by the 32Gbps limit of the DMI bus, allowing you to utilize CPU PCIe lanes to configure a bootable RAID array that can transfer data at insane speeds. Pro WS C422-ACE supports RAID 0, 1, 5, 10 to provide fault tolerance and improve overall performance.

    *A VROC key is required to enable VROC RAID arrays and support RAID 5 and 10, otherwise only RAID 0 and 1 are supported without a VROC key
    Trusted Stability

    Trusted Stability

    Pro WS C422-ACE provides enhanced features to smooth your IT operations, including comprehensive system protection, 24/7 stability and reliability.

    Ultra-efficient MOS & PCH heatsink

    Pro WS C422-ACE ensures optimal cooling and system stability for the Intel® Xeon® W Processors. Higher power requirements are balanced by carefully designed heatsinks that carefully balance mass and surface area to maximize thermal dissipation. In addition to the VRM-heatsink array and the heatpipe that's positioned to provide maximum airflow within the chassis, a dedicated heatsink also help to efficiently dissipate heat from the PCH.

    24/7 Dependability

    Quality reliability test

    Optimized for twenty-four seven operations, the motherboard is tested under temperature up to 45°C and humidity up to 80% to ensure it can handle diverse temperature and humidity range of different location.


    Protect your graphics card investment

    SafeSlot is the PCIe slot reinvented by ASUS and engineered to provide superior retention and shearing resistance. Manufactured in a single step using an insert-molding process, SafeSlot integrates the slot with fortifying metal for an inherently stronger slot, which is then firmly anchored to the PCB through additional solder points.

    Cooler by design

    Flexible cooling controls

    Pro WS C422-ACE features the most comprehensive cooling controls ever, configurable via Fan Xpert 4 or the UEFI BIOS.

    Each header can be set to monitor and react to three thermal sensors, and Fan Xpert 4 allows you to assign a sensor to monitor the temperature of supported ASUS graphics cards — all to provide optimal cooling during GPU- or CPU-intensive workloads.

    Dedicated PWM/DC header for self-contained water-cooling setup, built right in.

    Each onboard header supports auto-detection of PWM or DC fans.

    A dedicated integrated circuit protects each fan header from over-temperature and over-current.

    Server-grade IT management

    ASUS Control Center Express

    A server-grade IT management software

    ASUS Control Center Express is centralized server-grade IT management software that takes just only a few minutes to install and is designed to reduce IT operations costs and improve efficiency. This powerful tool enables IT administrators to manage and control multiple clients in different locations remotely and includes features such as asset management, software deployment and monitoring. ASUS Control Center Express also lets IT staff visualize deployments, facilitating real-time control.

    Quick installation
    Intuitive user interface
    Automatic IP detection
    Adaptive floor-plan design

    USB 3.2 Gen 2 back-panel connectors

    Future-proof connectivity

    The back panel of the Pro WS C422-ACE features four USB 3.2 Gen 2 connectors, including one reversible Type-C™ and three backward-compatible Type-A to deliver ultimate connection flexibility and blazing data-transfer speeds of up to 10Gbps.

    5-Way Optimization

    One-click overclock and cooling

    ASUS 5-Way Optimization makes your PC smart. One click takes care of complex tuning, dynamically optimizing essential aspects of your system to provide overclocking and cooling profiles that are tailored for your rig.

    An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.

    Fans stay whisper-quiet with everyday computing, and deliver optimal airflow when the system is crunching through CPU or GPU-intensive tasks.

    Stress test function helps optimize and overclock for CPU- or memory-centric workloads.

    CPU performance boost

    The TurboV Processing Unit (TPU) is the intelligence behind our automated system-tuning utility, offering the ability to fine-tune voltages, monitor system stats, and adjust overclock parameters for optimal performance.

    All-round energy efficiency

    With the Energy Processing Unit (EPU) you'll enjoy system-wide power savings. The EPU automatically optimizes power consumption and maximizes savings with Away mode — a smart setting that creates an extreme energy-saving scenario by shutting down unused I/O controllers.

    Flexible cooling controls for air or liquid

    With Pro WS C422-ACE you have comprehensive control over fans via Fan Expert 4 or our media-acclaimed UEFI. Whether you're cooling with air or water, Auto-Tuning mode intelligently configures all parameters with a single click. There's also an Extreme Quiet mode, which reduces all fan speeds to below the default minimum — keeping your system whisper-quiet when performing light tasks.

    Precise digital power control

    Digi+ delivers real-time control over voltage droop, switching frequency and power -efficiency settings, allowing you to fine-tune CPU voltage regulation for ultimate stability and performance.

    Scalable Expandability

    Ready for Intel® Xeon® W processors This motherboard supports Intel® Xeon® W Processors up to 18 cores to deliver Workstation Reliability, Serviceability and Availability (RAS) with Intel® Turbo Boost Max Technology 3.0, Intel® Hyper-Threading Technology, Intel® Rapid Storage Technology enterprise 5.0, Intel® Virtual RAID on Chip (Intel® VROC) and 4-channel DDR4-2933 ECC memory. This motherboard is purpose-built for 2D/3D CAD, BIM, and VR content development and ideal for the build of a HEDT.